Mid-size Drugs Based on Peptides and Peptidomimetics

Mid-size Drugs Based on Peptides and Peptidomimetics
Author : Hirokazu Tamamura
Publisher : Springer
Total Pages : 100
Release : 2018-01-25
ISBN 10 : 9811076901
ISBN 13 : 9789811076909
Language : EN, FR, DE, ES & NL

This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents. Peptides are important biological molecules and have various physiological actions. Peptide-based drug discovery may help bring about the development of useful medicines that are highly safe and show potent pharmacological effects in small doses. Recently, it has been shown that there is an important drug-like space in the mid-sized region between low- and high-molecular-weight compounds. Thus, mid-size drugs such as peptide compounds are being focused on. To date, several peptidomimetics that mimic primary, secondary, and tertiary structures of peptides have been developed to maintain and improve biological activities and actions of peptides. In this book, the features and advantages of mid-size drugs are described in detail. In addition, the merits of utilizing peptidomimetics in the development of mid-size drugs are referred to. Understanding such peptide-derived mid-size drugs will lead to a comprehensive expansion of medicinal chemistry.

Mid-size Drugs Based on Peptides and Peptidomimetics
Language: en
Pages: 100
Authors: Hirokazu Tamamura
Categories: Science
Type: BOOK - Published: 2018-01-25 - Publisher: Springer

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This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents. Pepti
Mid-size Drugs Based on Peptides and Peptidomimetics
Language: en
Pages: 100
Authors: Hirokazu Tamamura
Categories: Science
Type: BOOK - Published: 2018-01-16 - Publisher: Springer

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This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents. Pepti
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Type: BOOK - Published: 2014-03-14 - Publisher: John Wiley & Sons

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A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity.
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